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What is CKD-associated Pruritus?

Chronic kidney disease-associated pruritus ( CKD-associated Pruritus) is a troubling, and in some cases debilitating, condition that affects haemodialysis (HD) patients.1

The pruritus that patients experience is frequently persistent, which dramatically reduces patients’ quality-of-life and in severe cases is associated with an increase in mortality.2,3

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CKD-associated Pruritus, chronic kidney disease-associated pruritus; HD, haemodialysis; IV, intravenous; KORs, kappa-opioid receptors.

*In China, Korea and Japan further products are available and indicated for the treatment of CKD-associated Pruritus.

References:

  1. Verduzco HA & Shirazian S. Kidney Int Re. 2020;5:1387–1402.
  2. Pisoni RL, et al. Nephrol Dial Transplant. 2006;21:3495–3505.
  3. Sukul N, et al. Kidney Medicine. 2020;3(1):42–53.
  4. Albert-Vartanian A, et al. Journal of Clinical Pharmacy and Therapeutics. 2016;41:371–382.
  5. KAPRUVIA® Summary of Product Characteristics, 2022.
  6. Topf 2021 TBC (pooled manuscript).
  7. Fishbane S, et al. New Engl J Med. 2020;382:222–232.

  8. Fishbane S, et al. NKF 2021 Spring Clinical Meetings; Abstract 87 and poster presentation.

Address

Vifor Pharma Management Ltd.

Flughofstrasse 61
P.O. Box
8152 Glattbrugg
Switzerland

HQ-DFK-2300147  |  Date of preparation: October 2023

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